To save the tablet and the exhibits, Larry, along with his friends Teddy Roosevelt (Owen Wilson), Attila the Hun (Patrick Gallagher), and Sacagawea (Mizuo Peck), embark on a quest to find the secret of the tomb, which holds the key to the tablet's power. Along the way, they are joined by Dr. Marlow (Steve Coogan), a British historian, and Amelia Earhart (Amy Adams), a famous aviator.